Effects of IL-4 and IL-13 on total and allergen specific IgE production by cultured PBMC from allergic patients determined with recombinant pollen allergens.

BACKGROUND: Interleukin (IL)-4 and IL-13 have been shown to be potent switch factors for IgE synthesis in human B cells. OBJECTIVE: In this study we investigated the effects of recombinant human IL-4 and IL-13 on total and allergen specific IgE synthesis by peripheral blood mononuclear cells (PBMC)...

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Bibliographic Details
Main Authors: Dolecek, C, Steinberger, P, Susani, M, Kraft, D, Valenta, R, Boltz-Nitulescu, G
Format: Journal article
Language:English
Published: 1995