Reversal of phenotypes of cellular senescence by pan-mTOR inhibition
Cellular senescence, a state of essentially irreversible proliferation arrest, serves as a potent tumour suppressor mechanism. However, accumulation of senescent cells with chronological age is likely to contribute to loss of tissue and organ function and organismal aging. A crucial biochemical modu...
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| Format: | Journal article |
| Published: |
Impact Journals
2016
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