Non-competitive cyclic peptides for targeting enzyme-substrate complexes

Affinity reagents are of central importance for selectively identifying proteins and investigating their interactions. We report on the development and use of cyclic peptides, identified by mRNA display-based RaPID methodology, that are selective for, and tight binders of, the human hypoxia inducibl...

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Bibliographic Details
Main Authors: Mcallister, T, Yeh, T, Abboud, M, Leung, I, Hookway, E, King, O, Bhushan, B, Williams, S, Hopkinson, R, Muenzel, M, Loik, N, Chowdhury, R, Oppermann, U, Claridge, T, Goto, Y, Suga, H, Schofield, C, Kawamura, A
Format: Journal article
Published: Royal Society of Chemistry 2018