Effect of statins on bone mineral density and bone histomorphometry in rodents.

Statins have been postulated to affect bone metabolism. We investigated the effects of different doses of simvastatin (1, 5, 10, and 20 mg. kg(-1). d(-1)), atorvastatin (2.5 mg. kg(-1). d(-1)), and pravastatin (10 mg. kg(-1). d(-1)) administered orally for 12 weeks to intact female Sprague-Dawley ra...

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Bibliographic Details
Main Authors: Maritz, F, Conradie, M, Hulley, P, Gopal, R, Hough, S
Format: Journal article
Language:English
Published: 2001