Biodistribution and pharmacokinetic studies of a porphyrin dimer photosensitizer (Oxdime) by fluorescence imaging and spectroscopy in mice bearing xenograft tumors

Herein, we present a study of the pharmacokinetics and biodistribution of a butadiyne-linked conjugated porphyrin dimer (Oxdime) designed to have high near-infrared (NIR) 2-photon absorption cross-section for photodynamic therapy (PDT). Changes in biodistribution over time were monitored in mice car...

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Bibliographic Details
Main Authors: Khurana, M, Ulrich, S, Kim, A, Moriyama, Y, Netchev, G, Akens, M, Anderson, H, Wilson, B
Format: Journal article
Language:English
Published: 2012