Skewed X-inactivation is common in the general female population

X-inactivation is a well-established dosage compensation mechanism ensuring that X-chromosomal genes are expressed at comparable levels in males and females. Skewed X-inactivation is often explained by negative selection of one of the alleles. We demonstrate that imbalanced expression of the paterna...

ver descrição completa

Detalhes bibliográficos
Main Authors: Shvetsova, E, Sofronova, A, Monajemi, R, Gagalova, K, Draisma, H, White, S, Santen, G, Chuva De Sousa Lopes, S, Heijmans, B, Van Meurs, J, Jansen, R, Franke, L, Kiełbasa, S, Den Dunnen, J, 'T Hoen, P, Palamara, P
Outros Autores: Bios Consortium
Formato: Journal article
Idioma:English
Publicado em: Springer Nature 2018