Long-term persistence of gene expression from adeno-associated virus serotype 5 in the mouse airways.

Recombinant adeno-associated virus vectors based on serotype 2 (rAAV2) have been used to deliver transgenes to the airways in a variety of pre-clinical and clinical studies. Gene transfer in these studies has been severely restricted by the basolateral localization of rAAV2 receptors. Here, we studi...

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Autori principali: Sumner-Jones, S, Davies, L, Varathalingam, A, Gill, DR, Hyde, S
Natura: Journal article
Lingua:English
Pubblicazione: 2006