miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis.

miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis.

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BACKGROUND: Clear cell renal cancer frequently harbours von Hippel-Lindau (VHL) gene mutations, leading to stabilisation of the hypoxia-inducible factors (HIFs) and expression of their target genes. We investigated HIF-1 and HIF-2 in the regulation of microRNA-210 (miR-210), and its clinical relevan...

Podrobná bibliografie
Hlavní autoři:	McCormick, R, Blick, C, Ragoussis, J, Schoedel, J, Mole, D, Young, A, Selby, P, Banks, R, Harris, A
Médium:	Journal article
Jazyk:	English
Vydáno:	2013

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