CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in vivo is critical for bystander regulation.

The importance of CD25(+)CD4(+) regulatory T (Treg) cells in the control of immune responses is established, but their antigen specificity in vivo remains unclear. Understanding Treg-cell specificity requirements will be important if their potential is to be developed for immunotherapy. Pretreatment...

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Detaylı Bibliyografya
Asıl Yazarlar: Karim, M, Feng, G, Wood, K, Bushell, A
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2005