Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer.
Homodimerization of the membrane-bound collagenase MT1-MMP [membrane-type 1 MMP (matrix metalloproteinase)] is crucial for its collagenolytic activity. However, it is not clear whether this dimerization is regulated during cellular invasion into three-dimensional collagen matrices. To address this q...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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