Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer.

Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer.

Homodimerization of the membrane-bound collagenase MT1-MMP [membrane-type 1 MMP (matrix metalloproteinase)] is crucial for its collagenolytic activity. However, it is not clear whether this dimerization is regulated during cellular invasion into three-dimensional collagen matrices. To address this q...

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Bibliographic Details
Main Authors:	Itoh, Y, Palmisano, R, Anilkumar, N, Nagase, H, Miyawaki, A, Seiki, M
Format:	Journal article
Language:	English
Published:	2011

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