Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer.

Homodimerization of the membrane-bound collagenase MT1-MMP [membrane-type 1 MMP (matrix metalloproteinase)] is crucial for its collagenolytic activity. However, it is not clear whether this dimerization is regulated during cellular invasion into three-dimensional collagen matrices. To address this q...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Itoh, Y, Palmisano, R, Anilkumar, N, Nagase, H, Miyawaki, A, Seiki, M
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2011