Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer.

Homodimerization of the membrane-bound collagenase MT1-MMP [membrane-type 1 MMP (matrix metalloproteinase)] is crucial for its collagenolytic activity. However, it is not clear whether this dimerization is regulated during cellular invasion into three-dimensional collagen matrices. To address this q...

Повний опис

Бібліографічні деталі
Автори: Itoh, Y, Palmisano, R, Anilkumar, N, Nagase, H, Miyawaki, A, Seiki, M
Формат: Journal article
Мова:English
Опубліковано: 2011