5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

5-Hydroxymethylcytosine (5hmC) is an important mammalian DNA epigenetic modification that has been linked to gene regulation and cancer pathogenesis. Here we explored the diagnostic potential of 5hmC in circulating cell-free DNA (cfDNA) using a sensitive chemical labeling-based low-input shotgun seq...

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Bibliographic Details
Main Authors:	Song, C, Yin, S, Ma, L, Wheeler, A, Chen, Y, Zhang, Y, Liu, B, Xiong, J, Zhang, W, Hu, J, Zhou, Z, Dong, B, Tian, Z, Jeffrey, S, Chua, M, So, S, Li, W, Wei, Y, Diao, J, Xie, D, Quake, S
Format:	Journal article
Published:	Springer Nature 2017

5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

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