Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load.

Distinct IFN-gamma and IL-2 profiles of Ag-specific CD4(+) T cells have recently been associated with different clinical disease states and Ag loads in viral infections. We assessed the kinetics and functional profile of Mycobacterium tuberculosis Ag-specific T cells secreting IFN-gamma and IL-2 in...

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Bibliographic Details
Main Authors: Millington, K, Innes, J, Hackforth, S, Hinks, T, Deeks, J, Dosanjh, D, Guyot-Revol, V, Gunatheesan, R, Klenerman, P, Lalvani, A
Format: Journal article
Language:English
Published: 2007