Label-free, all-optical detection, imaging, and tracking of a single protein

Optical detection of individual proteins requires fluorescent labeling. Cavity and plasmonic methodologies enhance single molecule signatures in the absence of any labels but have struggled to demonstrate routine and quantitative single protein detection. Here, we used interferometric scattering mic...

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Detalhes bibliográficos
Principais autores: Arroyo, J, Andrecka, J, Spillane, KM, Billington, N, Takagi, Y, Sellers, JR, Kukura, P
Formato: Journal article
Idioma:English
Publicado em: American Chemical Society 2014