Label-free, all-optical detection, imaging, and tracking of a single protein

Optical detection of individual proteins requires fluorescent labeling. Cavity and plasmonic methodologies enhance single molecule signatures in the absence of any labels but have struggled to demonstrate routine and quantitative single protein detection. Here, we used interferometric scattering mic...

Full description

Bibliographic Details
Main Authors: Arroyo, J, Andrecka, J, Spillane, KM, Billington, N, Takagi, Y, Sellers, JR, Kukura, P
Format: Journal article
Language:English
Published: American Chemical Society 2014