The making and breaking of SAS-6: structural insights and inhibitor search for n-terminal domain dimerisation
<p>SAS-6 is the structural core of the forming centriole - a cylindrical protein complex, which is an essential component of the centrosome. Oligomerisation of SAS-6 is crucial for successful centriole duplication and is achieved through two dimerisation domains in the SAS-6 protein; a long C-...
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| Format: | Thesis |
| Language: | English |
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2017
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