The making and breaking of SAS-6: structural insights and inhibitor search for n-terminal domain dimerisation

The making and breaking of SAS-6: structural insights and inhibitor search for n-terminal domain dimerisation

<p>SAS-6 is the structural core of the forming centriole - a cylindrical protein complex, which is an essential component of the centrosome. Oligomerisation of SAS-6 is crucial for successful centriole duplication and is achieved through two dimerisation domains in the SAS-6 protein; a long C-...

Bibliografske podrobnosti
Glavni avtor:	Busch, J
Drugi avtorji:	Vakonakis, I
Format:	Thesis
Jezik:	English
Izdano:	2017
Teme:	Computational biology Structural Biology Biochemistry Biophysics

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