Enantioselective synthesis of atropisomeric indoles via iron-catalysed oxidative cross-coupling

Heterobiaryl compounds that exhibit axial chirality are of increasing value and interest across several fields, but direct oxidative methods for their enantioselective synthesis remain elusive. Here we disclose that an iron catalyst in the presence of a chiral PyBOX ligand and an oxidant enables dir...

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Detalhes bibliográficos
Main Authors: Surgenor, RR, Liu, X, Keenlyside, MJH, Myers, W, Smith, MD
Formato: Journal article
Idioma:English
Publicado em: Springer Nature 2022