Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design
Background: Development of countermeasures to bioterrorist threats such as those posed by the smallpox virus (variola), include vaccination and drug development. Selective activation of nucleoside analogues by virus-encoded thymidine (dThd) kinases (TK) represents one of the most successful strategi...
Asıl Yazarlar: | , , , , |
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Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
BioMed Central
2006
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Konular: |