Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design

Background: Development of countermeasures to bioterrorist threats such as those posed by the smallpox virus (variola), include vaccination and drug development. Selective activation of nucleoside analogues by virus-encoded thymidine (dThd) kinases (TK) represents one of the most successful strategi...

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Үндсэн зохиолчид: El Omari, K, Solaroli, N, Karlsson, A, Balzarini, J, Stammers, D
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: BioMed Central 2006
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