Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design
Background: Development of countermeasures to bioterrorist threats such as those posed by the smallpox virus (variola), include vaccination and drug development. Selective activation of nucleoside analogues by virus-encoded thymidine (dThd) kinases (TK) represents one of the most successful strategi...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
BioMed Central
2006
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| Subjects: |