Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes

Specific myeloid-related and inositide-specific gene mutations can be linked to myelodysplastic syndromes (MDS) pathogenesis and therapy. Here, 44 higher-risk MDS patients were treated with azacitidine and lenalidomide and mutations analyses were performed at baseline and during the therapy. Results...

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Bibliographic Details
Main Authors: Follo, M, Pellagatti, A, Armstrong, R, Ratti, S, Mongiorgi, S, De Fanti, S, Bochicchio, M, Russo, D, Gobbi, M, Miglino, M, Parisi, S, Martinelli, G, Cavo, M, Luiselli, D, McCubrey, J, Suh, P, Manzoli, L, Boultwood, J, Finelli, C, Cocco, L
Format: Journal article
Language:English
Published: Springer Nature 2019