HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound.

HIV-specific CD4+ T helper lymphocytes are preferred targets for infection. Although complete interruption of combination antiretroviral therapy (ART) can form part of therapeutic manipulations, there is grave concern that the resumption of viral replication might destroy, perhaps irreversibly, thes...

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Bibliographic Details
Main Authors: Scriba, T, Zhang, H, Brown, H, Oxenius, A, Tamm, N, Fidler, S, Fox, J, Weber, J, Klenerman, P, Day, C, Lucas, M, Phillips, R
Format: Journal article
Language:English
Published: 2005