Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein

The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA double helix. An initial and essential stage in the repair process is the detection of the ICL. Here, we report the identification of UHRF2, a paralogue of UHRF1, as a...

Полное описание

Библиографические подробности
Главные авторы: Motnenko, A, Liang, C, Yang, D, Lopez-Martinez, D, Yoshikawa, Y, Zhan, B, Ward, K, Tian, J, Haas, W, Spingardi, P, Kessler, B, Kriaucionis, S, Gygi, S, Cohn, M
Формат: Journal article
Опубликовано: Public Library of Science 2018