Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein
The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA double helix. An initial and essential stage in the repair process is the detection of the ICL. Here, we report the identification of UHRF2, a paralogue of UHRF1, as a...
Главные авторы: | , , , , , , , , , , , , , |
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Формат: | Journal article |
Опубликовано: |
Public Library of Science
2018
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