Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression

<h4>Objectives</h4> <p>Tristetraprolin (TTP), a negative regulator of many pro-inflammatory genes, is strongly expressed in rheumatoid synovial cells. The mitogen-activated protein kinase (MAPK) p38 pathway mediates the inactivation of TTP via phosphorylation of two serine residue...

Full description

Bibliographic Details
Main Authors:	Ross, E, Naylor, A, O'Neil, J, Crowley, T, Ridley, M, Crowe, J, Smallie, T, Tang, T, Turner, J, Norling, L, Dominguez, S, Perlman, H, Verrills, N, Kollias, G, Vitek, M, Filer, A, Buckley, C, Dean, J, Clark, A
Format:	Journal article
Language:	English
Published:	BMJ Publishing Group 2016

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression

Similar Items