Exposing viruses: RNA patterns sensed by RIG-I-like receptors.

INTRODUCTION: Virus infection triggers a multitude of innate immune pathways that limit viral replication, restrict viral spread and coordinate antigen-specific, adaptive immune responses. Type-I interferons (IFNs) play a crucial role in these events. Innate receptors expressed by the host cell rec...

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Bibliographic Details
Main Author: Rehwinkel, J
Format: Journal article
Language:English
Published: 2010