Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.

Genetic recombination contributes to the diversity of human immunodeficiency virus (HIV-1). Productive HIV-1 recombination is, however, dependent on both the number of HIV-1 genomes per infected cell and the genetic relationship between these viral genomes. A detailed analysis of the number of provi...

Full description

Bibliographic Details
Main Authors: Josefsson, L, Palmer, S, Faria, N, Lemey, P, Casazza, J, Ambrozak, D, Kearney, M, Shao, W, Kottilil, S, Sneller, M, Mellors, J, Coffin, J, Maldarelli, F
Format: Journal article
Language:English
Published: Public Library of Science 2013