Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells

The development of an efficacious vaccine against the Plasmodium parasite remains a top priority. Previous research has demonstrated the ability of a prime-boost virally vectored sub-unit vaccination regimen, delivering the liver-stage expressed malaria antigen TRAP, to produce high levels of antige...

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Bibliographic Details
Main Authors: Longley, R, Bauza, K, Ewer, K, Hill, A, Spencer, A
Format: Journal article
Language:English
Published: Public Library of Science 2015