Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis.

Tumor-infiltrating immune cells play important roles in metastasis. We have recently revealed the recruitment of a specific myeloid cell subset (CD11b/Gr1(mid)) to hepatic metastases. Such a recruitment relies on CCL2/CCR2 signaling and acts to sustain metastatic growth. A similar cell subset was id...

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Bibliographic Details
Main Authors: Lim, S, Gordon-Weeks, A, Zhao, L, Tapmeier, T, Im, J, Cao, Y, Beech, J, Allen, D, Smart, S, Muschel, R
Format: Journal article
Language:English
Published: 2013