Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Lopez-Martinez, D, Liang, C, Cohn, M
Fformat: Journal article
Cyhoeddwyd: Springer Verlag 2016