Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Lopez-Martinez, D, Liang, C, Cohn, M
التنسيق: Journal article
منشور في: Springer Verlag 2016

مواد مشابهة