Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Lopez-Martinez, D, Liang, C, Cohn, M
Format:	Journal article
Udgivet:	Springer Verlag 2016

Lignende værker

UHRF1 Is a sensor for DNA interstrand crosslinks and recruits FANCD2 to initiate the Fanconi Anemia pathway
af: Liang, C, et al.
Udgivet: (2015)

UHRF1 Is a Sensor for DNA Interstrand Crosslinks and Recruits FANCD2 to Initiate the Fanconi Anemia Pathway
af: Chih-Chao Liang, et al.
Udgivet: (2015-03-01)

UHRF1 is a sensor for DNA interstrand crosslinks.
af: Cohn, M, et al.
Udgivet: (2016)

Elevated levels of STAT1 in Fanconi anemia group A lymphoblasts correlate with the cells’ sensitivity to DNA interstrand crosslinking drugs
af: Inés Prieto-Remón, et al.
Udgivet: (2013-05-01)

Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast
af: Ward, T, et al.
Udgivet: (2012)

Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.
af: Thomas A Ward, et al.
Udgivet: (2012-01-01)

WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair
af: Socha, A, et al.
Udgivet: (2020)

The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks prior to monoubiquitination of FANCD2
af: Liang, C, et al.
Udgivet: (2016)

Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway
af: Niyo Kato, et al.
Udgivet: (2017-10-01)

Ouabain, a cardiac glycoside, inhibits the Fanconi anemia/BRCA pathway activated by DNA interstrand cross-linking agents.
af: Dong Wha Jun, et al.
Udgivet: (2013-01-01)

Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein
af: Motnenko, A, et al.
Udgivet: (2018)

Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein.
af: Anna Motnenko, et al.
Udgivet: (2018-10-01)

The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2
af: Chih-Chao Liang, et al.
Udgivet: (2016-07-01)

Genetic inactivation of the Fanconi anemia gene <it>FANCC </it>identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand crosslinking agents
af: Bassermann Florian, et al.
Udgivet: (2010-05-01)

The role of PARPs and APLF in DNA interstrand crosslink repair
af: Zobel, F
Udgivet: (2017)

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair
af: Gunn, A, et al.
Udgivet: (2016)

Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA
af: Qiuzhen Li, et al.
Udgivet: (2021-06-01)

Studies of the Fanconi anemia pathway
af: Liang, C
Udgivet: (2016)

The 13th Fanconi Anemia Gene Identified: FANCI – Importance of the ‘Fanconi Anemia Pathway’ for Cellular Oncology
af: Gerrit A. Meijer
Udgivet: (2007-01-01)

FANCD2 and CtIP Cooperate to Repair DNA Interstrand Crosslinks
af: Olga Murina, et al.
Udgivet: (2014-05-01)

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.
af: Iyama, T, et al.
Udgivet: (2015)

Phosphorylation of FANCD2 inhibits the FANCD2/FANCI complex and suppresses the Fanconi anemia pathway in the absence of DNA damage
af: Lopez-Martinez, D, et al.
Udgivet: (2019)

Understanding the genetic relationship between key effectors of DNA interstrand crosslink repair
af: Brolih, S
Udgivet: (2016)

Single Molecule Analysis of Laser Localized Interstrand Crosslinks
af: Jing eHuang, et al.
Udgivet: (2016-05-01)

Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.
af: Cohn, M, et al.
Udgivet: (2008)

RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.
af: Abdullah, U, et al.
Udgivet: (2017)

RPA activates the XPF‐ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks
af: Abdullah, U, et al.
Udgivet: (2017)

Targeting interstrand crosslink repair to improve chemotherapeutic strategies
af: Castle, L
Udgivet: (2017)

Replication fork reversal during DNA interstrand crosslink repair requires CMG unloading
af: Amunugama, R, et al.
Udgivet: (2018)

Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage.
af: Xiaojuan Zhang, et al.
Udgivet: (2021-07-01)

Uncovering roles of proteins in the Fanconi Anemia DNA repair pathway
af: Xu, H
Udgivet: (2024)

Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage
af: David Lopez-Martinez, et al.
Udgivet: (2019-06-01)

DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway
af: Sonali Bhattacharjee, et al.
Udgivet: (2017-10-01)

Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
af: Kupculak, M, et al.
Udgivet: (2023)

Visualizing Inhibition of Nucleosome Mobility and Transcription by Cisplatin-DNA Interstrand Crosslinks in Live Mammalian Cells
af: Zhu, Guangyu, et al.
Udgivet: (2014)

Identification of novel players implicated in replication-dependent and independent DNA interstrand crosslink (ICL) repair
af: Yaprianto, K
Udgivet: (2021)

Interstrand crosslinking oligonucleotides elucidate the effect of metal ions on the methylation status of repetitive DNA elements
af: Shan Liu, et al.
Udgivet: (2023-01-01)

Regulation of the Fanconi anemia DNA repair pathway by phosphorylation of FANCD2
af: Kupculak, M
Udgivet: (2020)

The Fanconi Anemia Pathway of Genomic Maintenance
af: Marieke Levitus, et al.
Udgivet: (2006-01-01)

DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta.
af: Sarkar, S, et al.
Udgivet: (2006)