Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

Bibliografske podrobnosti
Main Authors:	Lopez-Martinez, D, Liang, C, Cohn, M
Format:	Journal article
Izdano:	Springer Verlag 2016

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