Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

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Những tác giả chính:	Lopez-Martinez, D, Liang, C, Cohn, M
Định dạng:	Journal article
Được phát hành:	Springer Verlag 2016

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