The unconventional kinetoplastid kinetochore: from discovery toward functional understanding
The kinetochore is the macromolecular protein complex that drives chromosome segregation in eukaryotes. Its most fundamental function is to connect centromeric DNA to dynamic spindle microtubules. Studies in popular model eukaryotes have shown that CENP-A is critical for DNA-binding, while the Ndc80...
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Format: | Journal article |
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Portland Press
2016
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