Distinct patterns of expression of MHC class I and beta 2-microglobulin transcripts at early stages of mouse development.

The class I surface Ag recognized during tissue graft rejection are composed of a 40- to 45-kDa H chain and a 12-kDa L chain, beta 2-microglobulin (beta 2m). Regulation of MHC gene expression during early development is thought to play an essential role in maternal tolerance of the fetal allograft....

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Bibliographic Details
Main Authors: Jaffe, L, Robertson, E, Bikoff, E
Format: Journal article
Language:English
Published: 1991