Distinct patterns of expression of MHC class I and beta 2-microglobulin transcripts at early stages of mouse development.
The class I surface Ag recognized during tissue graft rejection are composed of a 40- to 45-kDa H chain and a 12-kDa L chain, beta 2-microglobulin (beta 2m). Regulation of MHC gene expression during early development is thought to play an essential role in maternal tolerance of the fetal allograft....
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1991
|