Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission.

A commonly occurring polymorphic variant of the human 5-hydroxytryptamine (5-HT) transporter (5-HTT) gene that increases 5-HTT expression has been associated with reduced anxiety levels in human volunteer and patient populations. However, it is not known whether this linkage between genotype and anx...

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Bibliographic Details
Main Authors: Jennings, K, Loder, M, Sheward, W, Pei, Q, Deacon, R, Benson, M, Olverman, H, Hastie, N, Harmar, A, Shen, S, Sharp, T
Format: Journal article
Language:English
Published: 2006