Scavenger receptor-mediated uptake of cell-penetrating peptide nanocomplexes with oligonucleotides.

Cell-penetrating peptides (CPPs) are short cationic peptides that penetrate cells by interacting with the negatively charged plasma membrane; however, the detailed uptake mechanism is not clear. In contrary to the conventional mode of action of CPPs, we show here that a CPP, PepFect14 (PF14), forms...

Full description

Bibliographic Details
Main Authors: Ezzat, K, Helmfors, H, Tudoran, O, Juks, C, Lindberg, S, Padari, K, El-Andaloussi, S, Pooga, M, Langel, U
Format: Journal article
Language:English
Published: 2012