The amino acid homoarginine inhibits atherogenesis by modulating T-cell function

Background: Amino acid metabolism is crucial for inflammatory processes during atherogenesis. The endogenous amino acid homoarginine is a robust biomarker for cardiovascular outcome and mortality with high levels being protective. However, the underlying mechanisms remain elusive. We investigated th...

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Bibliographic Details
Main Authors: Nitz, K, Lacy, M, Bianchini, M, Wichapong, K, Kücükgöze, IA, Bonfiglio, CA, Migheli, R, Wu, Y, Burger, C, Li, Y, Forné, I, Ammar, C, Janjic, A, Mohanta, S, Duchene, J, Heemskerk, JWM, Megens, RTA, Schwedhelm, E, Huveneers, S, Lygate, CA, Santovito, D, Zimmer, R, Imhof, A, Weber, C, Lutgens, E, Atzler, D
Format: Journal article
Language:English
Published: American Heart Association 2022