Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.

Human leukocyte antigen (HLA)-B27-positive subjects are uncommon in their ability to control infection with human immunodeficiency virus type 1 (HIV-1). However, late viral escape from a narrowly directed immunodominant Gag-specific CD8(+) T-lymphocyte (CTL) response has been linked to AIDS progress...

Full description

Bibliographic Details
Main Authors:	Schneidewind, A, Brockman, M, Yang, R, Adam, R, Li, B, Le Gall, S, Rinaldo, C, Craggs, S, Allgaier, R, Power, K, Kuntzen, T, Tung, C, LaBute, M, Mueller, S, Harrer, T, Mcmichael, A, Goulder, P, Aiken, C, Brander, C, Kelleher, A, Allen, T
Format:	Journal article
Language:	English
Published:	2007

Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.

Similar Items