Ribozyme-mediated trans-splicing of a trinucleotide repeat.
Trinucleotide repeat expansions (TREs) are a recently described class of mutations characterized by a change in the size of the genomic fragment due to amplification of the repeated unit. A number of diseases have been attributed to TRE, including Huntington disease and myotonic dystrophy (DM), but...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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