Second generation superagonistic anti-PD-1 antibodies

<p>Antibodies known as ‘superagonists’, such as those raised against CD28, induce high levels of signalling activity. Based on the kinetic-segregation model, a hypothesis arose: the greater potency of superagonists arises from their ability to more effectively exclude large phosphatases from t...

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Dettagli Bibliografici
Autore principale: Yu, SY
Altri autori: Davis, S
Natura: Tesi
Lingua:English
Pubblicazione: 2019
Soggetti: