Structural insights into chondroitin sulfate binding in pregnancy-associated malaria.
Malaria during pregnancy is caused when parasite-infected erythrocytes accumulate within the placenta through interactions between the VAR2CSA protein on the infected erythrocyte surface and placental CSPGs (chondroitin sulfate proteoglycans). This interaction is the major target for therapeutics to...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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