Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.
The endothelins are a family of endothelium-derived peptides that possess a variety of biological activities, including potent vasoconstriction. Endothelin-1 (ET-1) is up-regulated during tissue repair and pulmonary fibrosis. Here, we use genome-wide expression array analysis to show that the additi...
| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
2004
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