Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.

Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.

The endothelins are a family of endothelium-derived peptides that possess a variety of biological activities, including potent vasoconstriction. Endothelin-1 (ET-1) is up-regulated during tissue repair and pulmonary fibrosis. Here, we use genome-wide expression array analysis to show that the additi...

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Bibliographic Details
Main Authors:	Xu, S, Howat, S, Renzoni, E, Holmes, A, Pearson, J, Dashwood, MR, Bou-Gharios, G, Denton, C, du Bois, R, Black, C, Leask, A, Abraham, D
Format:	Journal article
Language:	English
Published:	2004

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