Why do some T cell receptor cytoplasmic domains associate with the plasma membrane?

Based on studies in model systems it has been proposed that the cytoplasmic domains of T cell receptor signaling subunits that have polybasic motifs associate with the plasma membrane, and that this regulates their phosphorylation. Recent experiments in more physiological systems have confirmed memb...

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Bibliographic Details
Main Authors: Van Der Merwe, P, Zhang, H, Cordoba, S
Format: Journal article
Language:English
Published: 2012