SUBSTRATE-SPECIFICITY OF PROLINE 4-HYDROXYLASE - CHEMICAL AND ENZYMATIC-SYNTHESIS OF 2S,3R,4S-EPOXYPROLINE

The substrate specificity of L-proline-4-hydroxylase, a 2-oxoglutarate dependent dioxygenase from Streptomyces griseoviridus P8648, was investigated. Preliminary assays measuring turnover of 2-oxoglutarate indicated 3,4-dehydro-L-proline was an efficient substrate. The identity of the product was sh...

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Bibliographic Details
Main Authors: Baldwin, J, Field, R, Lawrence, C, Lee, V, Robinson, J, Schofield, C
Format: Journal article
Language:English
Published: 1994