A protein particle vaccine containing multiple malaria epitopes.

Ty virus-like particles consist of a single protein species that can be produced in yeast. Recombinant Ty-VLPs carrying a string of up to 15 defined cytotoxic T lymphocyte (CTL) epitopes from Plasmodium species prime protective CTL responses in mice following a single administration without adjuvant...

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Bibliographic Details
Main Authors: Gilbert, S, Plebanski, M, Harris, S, Allsopp, C, Thomas, R, Layton, G, Hill, A
Format: Journal article
Language:English
Published: 1997