Development of clinical biomarkers of DNA double strand breaks for cancer care

<p>Many anticancer therapies, including radiotherapy, act by damaging the deoxyribosenucleic acid (DNA) that is fundamental to cell function and proliferation. H2AX is a histone protein associated with DNA that is phosphorylated to produce γH2AX in response to DNA double strand breaks (DSBs),...

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Bibliographic Details
Main Author: Shah, K
Other Authors: Vallis, K
Format: Thesis
Language:English
Published: 2012
Subjects: