Development of clinical biomarkers of DNA double strand breaks for cancer care

<p>Many anticancer therapies, including radiotherapy, act by damaging the deoxyribosenucleic acid (DNA) that is fundamental to cell function and proliferation. H2AX is a histone protein associated with DNA that is phosphorylated to produce γH2AX in response to DNA double strand breaks (DSBs),...

Полное описание

Библиографические подробности
Главный автор: Shah, K
Другие авторы: Vallis, K
Формат: Диссертация
Язык:English
Опубликовано: 2012
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