Development of clinical biomarkers of DNA double strand breaks for cancer care
<p>Many anticancer therapies, including radiotherapy, act by damaging the deoxyribosenucleic acid (DNA) that is fundamental to cell function and proliferation. H2AX is a histone protein associated with DNA that is phosphorylated to produce γH2AX in response to DNA double strand breaks (DSBs),...
Main Author: | Shah, K |
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Other Authors: | Vallis, K |
Format: | Thesis |
Language: | English |
Published: |
2012
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Subjects: |
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